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Streamflow-related variability in nutrient flux represents an important source of uncertainty in managing nutrient inputs to coastal ecosystems. Quantification of flux variability is of particular interest to coastal resource managers in adopting effective nutrient-reduction goals and monitoring progress towards these goals. We used historical records of streamflow and water-quality measurements for 104 river monitoring stations in an analysis of variability in annual and seasonal flux of nitrate to the Atlantic coastal zone. We present two measures of temporal flux variability: the coefficient of variation (CV) and the exceedence probability (EP) of 1.5 times the median flux. The magnitude of flux variations spans a very wide range and depends importantly upon the season of year and the climatic and land-use characteristics of the tributary watersheds. Year-to-year variations (CV) in annual mean flux range over two orders of magnitude, from 3–200% of the long-term mean flux, although variations more typically range from 20–40% of the long-term mean. The annual probability of exceeding the long-term median flux by more than 50% (EP) is less than 0.10 in most rivers, but is between 0.10 and 0.35 in 40% of the rivers. Year-to-year variability in seasonal mean flux commonly exceeds that in annual flux by a factor of 1.5 to 4. In western Gulf of Mexico coastal rivers, the year-to-year variablity in the seasonal mean flux is larger than in other regions, and is of a similar magnitude in all seasons. By contrast, in Atlantic coastal rivers, the winter and spring seasons, which account for about 70% of the annual flux, display the smallest relative variability in seasonal mean flux. We quantify the elasticity of nutrient flux to hypothetical changes in Streamflow (i.e., the percent increase in flux per percentage increase in mean discharge) to allow the approximation of flux variability from streamflow records and the estimation of the effects of future climatically-induced changes in Streamflow on nutrient flux. Flux elasticities are less than unity (median = 0.93%) at most stations, but vary widely from 0.05% to 1.59%. Elasticities above unity occur most frequently in the largest rivers and in rivers draining the arid portions of the western Gulf of Mexico Basin. Historical flux variability and elasticity generally increase with the extent of arid conditions and the quantity of nonurban land use in the watershed. We extend the analysis of flux variability to examine several case studies of highly unusual meteorological events capable of significantly elevating nitrate flux and degrading estuarine ecology.  相似文献   
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During the course of routine prenatal cytogenetics, a male with 2 different autosomal fragile sites (FS) was detected. The FS were at 9p21 and 12q13 and his sister also had both fragile sites, inherited from an obligate carrier father. He was the father of a foetus with an abnormal chromosome complement 46,XY/47,XY,+frag. The origin of the fragment could not be determined.  相似文献   
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In 2008, a well preserved and complete shoe was recovered at the base of a Chalcolithic pit in the cave of Areni-1, Armenia. Here, we discuss the chronology of this find, its archaeological context and its relevance to the study of the evolution of footwear. Two leather samples and one grass sample from the shoe were dated at the Oxford Radiocarbon Accelerator Unit (ORAU). A third leather sample was dated at the University of California-Irvine Accelerator Mass Spectrometry Facility (UCIAMS). The R_Combine function for the three leather samples provides a date range of 3627–3377 Cal BC (95.4% confidence interval) and the calibrated range for the straw is contemporaneous (3627–3377 Cal BC). The shoe was stuffed with loose, unfastened grass (Poaceae) without clear orientation which was more than likely used to maintain the shape of the shoe and/or prepare it for storage. The shoe is 24.5 cm long (European size 37), 7.6 to 10 cm wide, and was made from a single piece of leather that wrapped around the foot. It was worn and shaped to the wearer''s right foot, particularly around the heel and hallux where the highest pressure is exerted in normal gait. The Chalcolithic shoe provides solid evidence for the use of footwear among Old World populations at least since the Chalcolithic. Other 4th millennium discoveries of shoes (Italian and Swiss Alps), and sandals (Southern Israel) indicate that more than one type of footwear existed during the 4th millennium BC, and that we should expect to discover more regional variations in the manufacturing and style of shoes where preservation conditions permit.  相似文献   
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